Endocrine Abstracts

Introduction: Central precocious puberty (CPP) is a frequent reason for consultation in pediatrics. It is defined as the development of sexual characteristics before the age of 8 years in girls and 9 years in boys. Pediatric pituitary adenomas are rare. We report the case of a patient who presented with central precocious puberty on pituitary adenoma.Observation: This is a patient aged 7 years and 6 months, without any particular history, having consulte...

Introduction: Hashimoto’s encephalopathy or SREAT (steroid-responsive encephalopathy associated with auto-immune thyroiditis) is a rare autoimmune disorder that is particularly corticosensitive and whose pathogenesis remains poorly understood. It is associated with high levels of antithyroid antibodies in plasma and/or CSF. Clinical manifestations are deceptive and may include cognitive and behavioral disturbances, seizures or abnormal movements.Cas...

Introduction: Thevenard’s disease is a sensory neuropathy with a type of ulcerative-mutilating acropathy of progressive course. It has a hereditary character with autosomal dominant inheritance. It is a scarce disease, which usually affects feet but can also affect hands. It causes disorders of thermoalgesic sensitivity, leading to painless ulcerations at the pressure points and then bone deformities with osteoarticular destruction and ‘cubic foot‘ appearance. R...

Introduction: Gayet-Wernicke encephalopathy (WE) is a rare neurological disorder, caused by thiamine (vitamin B1) deficiency. We report a case of tertiary adrenal insufficiency revealing Gayet-Wernicke encephalopathy.Case presentation: A 45-year-old women was admitted with abdominal pain, vomiting and weakness. Her medical history was significant for a long-term self-medication with corticosteroids and chronic vomiting. Clinical examination revealed a cu...

Introduction: Pheochromocytoma (PHEO) is an adrenal medulla tumor secreting catecholamines. Malignancy is defined by the presence of metastases in non-chromaffin tissue. Its optimal management requires experienced multidisciplinary teams.We report the case of a patient followed for malignant pheochromocytomaComment: 58-year-old patient operated for a pheochromocytoma in 2016, then lost sight of. The evolution was marked 6 years later by the installation ...

Introduction: Brown tumors are osteolytic lesions rarely revealing hyperparathyroidism. They result from abnormalities of bone metabolism. They usually occur in the terminal stage of hyperparathyroidism. We report the case of a patient with hyperparathyroidism revealed by a brown tumor.Case: A 39-year-old female patient with no notable medical history who presented for 1 year a mandibular swelling progressively increasing in size after a dental extractio...

Introduction: Primary hyperparathyroidism (PPH) can be complicated by pancreatitis. The frequency of association of primary hyperparathyroidism with pancreatitis is rare, varying between 1.5% and 7%. We report the case of a patient with hyperparathyroidism revealed by acute pancreatitis.Case: A 78-year-old patient, without any particular history, who consulted the emergency room for an acute digestive picture with abdominal pain and bilious vomiting, an ...

Introduction: Postoperative hypoparathyroidism is a frequent complication of total thyroidectomy that must be detected and treated. The resulting hypocalcemia is quite severe and usually occurs in the first few days or weeks after surgery.Herein, we describe a case of chronic asymptomatic hypocalcemia related to postoperative hypoparathyroidism diagnosed years after total thyroidectomy.Observation: We report the case of a 61 year old woman, who had a tot...

Introduction: Lipoatrophy is a rare cutaneous complication in diabetes that presents with localized subcutaneous fat atrophy at the insulin injection site. We report a case of a 62-year-old man type 1 diabetic with lipoatrophy lesions on the thighs.Case report: A 62-year-old male, with clinical history of basedow’s disease, He was diagnosed type 1 diabetes (T1D) when he was 19 years old, treated with premixed human insulin for the last 4 years.His w...

Introduction: Hypertriglyceridemia (HTG) is a rare but well-known cause of acute pancreatitis, which can be fatal with an overall mortality rate of 36-50% in the most severe forms.Case presentation: A 29-year-old patient was admitted to the emergency department with abdominal pain, bilious vomiting and alteration of general condition. Physical examination showed hemodynamic shock with diffuse abdominal tenderness. The Laboratory results showed a serum li...